patent/EP-0239400-A2

http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0239400-A2

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Predicate	Object
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classificationCPCInventive	http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-464
classificationIPCAdditional	http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91
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filingDate	1987-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor	http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5f448ecd033515041484564f5221d26
publicationDate	1987-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber	EP-0239400-A2
titleOfInvention	Recombinant antibodies and methods for their production
abstract	An altered antibody is produced by replacing the complementarity determining regions (CDRs) of a variable region of an immunoglobulin (Ig) with the CDRs from an Ig of different specificity, using recombinant DNA techniques. The gene coding sequences for producing the altered antibody may be produced by site-directed mutagenesis using long oligonucleotides.
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