| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_872dd7cd609eb2a937dcfd303d521798 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-507 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eaee731c4cd1f60de0c80748af9e45b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c49294346cacdcc17445281c7ee84b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66e629c34fd75efb924ca45b3d60a974
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_636123d4bff7b881c6ea4d523981cd89 |
| publicationDate |
2018-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018225033-A1 |
| titleOfInvention |
Combination therapy |
| abstract |
The present invention provides methods of treating cancer in a patient in need thereof, the method comprising administering to the patient an effective amount of an agent directed to human ICOS and an effective amount of an agent directed to human PD 1 or human PD-Ll sequentially. The present invention also provides an anti-ICOS antibody or antigen binding fragment thereof and an anti-PD 1 antibody or antigen binding fragment thereof for sequential use in treating cancer in a human in need thereof. The present invention provides an anti- ICOS antibody or antigen binding fragment thereof and an anti-PD-Ll antibody or antigen binding fragment thereof for sequential use in treating cancer in a human in need thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11629189-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021209357-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021209358-A1 |
| priorityDate |
2017-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |