| abstract |
Nanoparticles and their uses in molecular imaging are disclosed that are formed from an inorganic ionic material capable of binding to an imaging probe and optionally linked to a primary targeting group for binding to a target in a biological system, for example an in vivo location in a subject undergoing molecular imaging. The nanoparticles may be used in a pre-targeting mode in which the nanoparticle is administered to a patient to reach the target of interest and is subsequently followed by administration of the imaging probe. In other aspects, nanoparticles are disclosed in which a fluorine radionuclide is directly bound to the nanoparticles |