Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9871e02d1c09cc338f51aecbb5510178 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
filingDate |
2014-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f9517320a062b90453b05b29c765a89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96c6c0847d80906d31ef2ea3aa583195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9674c784dba91edb9556fd50bd59d23c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b03c453db1545cef9b31a22114fd9b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2504681efbf9cba5a37d9c088de8ee4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56e0d063f45f80a12798011a6e9a5ff3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_699d1a564fffd37195b80182a4b5f05f |
publicationDate |
2018-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9963508-B2 |
titleOfInvention |
Human monoclonal antibodies to CTLA-4 |
abstract |
In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11319377-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10449251-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11479608-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11291720-B2 |
priorityDate |
1998-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |