| abstract |
The present invention is related to monoclonal antibodies, fragments, antigen binding portions or fragments thereof, for specific binding to human and/or mouse tumor associated carbohydrate antigens expressed on cancer cells, e.g., human colorectal adenocarcinma, non-small cell lung carcinoma (NSCLC). These antibodies can be used to induce selective cell death in cancer cells and for the treatment of cancer, e.g., NSCLC and/or in the diagnosis of cancers expressing tumor associated carbohydrate antigens in-vitro and in-vivo. |