Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a09ca043d7e596facff1f44b746e2f4d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1063 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10 |
filingDate |
1993-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1998-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93e491c2bef03c38afd6c82058361c83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0020b8a7b26abf06370c8798bda8c25a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e939b268ed34f1e5d3f10ca306018b07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c7a156ba01f046a784eef19dd2c4c81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f53c2c500c9ef279960c6eae91cc41e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fab35b4bb9462102a9ed646f34fd5fd |
publicationDate |
1998-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5773247-A |
titleOfInvention |
Recombinant anti-HIV antibody and process for preparing the same |
abstract |
The present invention relates to a gene fragment coding for a variable region of an antibody having a neutralizing activity against human immunodeficiency virus (HIV) and a process for preparing the same. A mouse-human chimeric antibody and a mouse-human reshaped antibody having a neutralizing activity against HIV can be prepared by obtaining a specific nucleotide sequence of a gene fragment coding for a variable region of H chain and L chain of an antibody having a neutralizing activity against HIV, and then artificially fusing DNAs synthesized based on these nucleotide sequences with a gene coding for a human immunoglobulin. The novel recombinant anti-HIV antibody of the present invention is useful for treatment and prevention of AIDS. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7744878-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7563437-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003108966-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-025245-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007128202-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004171814-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2586461-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3069730-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3072901-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3187585-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2873423-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005245454-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003180326-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2679596-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2568289-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3150223-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7405061-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7148038-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012170765-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2848937-A1 |
priorityDate |
1993-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |