| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a09ca043d7e596facff1f44b746e2f4d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1063
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
1989-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e939b268ed34f1e5d3f10ca306018b07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93e491c2bef03c38afd6c82058361c83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b1527bc6f75e8fd4b7fa3f01393996f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fab35b4bb9462102a9ed646f34fd5fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f53c2c500c9ef279960c6eae91cc41e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23abe24afb395e456e57a988918c2d8d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24239cc18816d0ceeb26586b3f99eff2 |
| publicationDate |
1989-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0327000-A2 |
| titleOfInvention |
Gene fragments coding for the variable region of an anti-HIV antibody, chimeric anti-HIV antibodies expressed using the same, and process for their preparation |
| abstract |
Described are novel chimeric anti-human immunodeficiency virus (HIV) antibodies which comprise a constant region derived from human antibody and variable region derived from mouse monoclonal antibody, gene fragments coding for the variable region the H and L chain of chimeric anti-HIV antibodies which are effective for expression of chimeric anti-HIV antibodies having an HIV-neutralizing activity, a transformant where such gene fragments are incorporated, chimeric anti-HIV antibodies expressed therefrom and a process for their preparation. The chimeric anti-HIV antibodies of the present invention show anti-HIV neutralizing activity and are useful for the diagnosis, treatment and prevention of acquired immunodeficiency syndrome (AIDS) caused by HIV without side effects such as anaphylactic shock or serum sickness. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5914110-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5928904-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7807793-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8075890-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0453554-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0453554-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0453561-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0699755-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5773247-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6719971-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0730609-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6800738-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0453561-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE46877-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7098006-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0730609-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6797492-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE43898-E |
| priorityDate |
1988-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |