| abstract |
A compound having the structure: <IMAGE> wherein R1 is an oligonucleotide; a is 1 and b is 0; A is C or CH; X is S, O, NH or NCH2R6; Z is taken together with A to form an aryl ring structure comprising 6 ring atoms wherein the aryl ring carbon atoms are unsubstituted with other than H or at least 1 nonbridging ring carbon atom is substituted with R6 or =O; R6 is independently H, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, NO2, N(R3)2, C 3BOND N or halo, or an R6 is taken together with an adjacent Z group R6 to complete a phenyl ring; and R3 is a protecting group or H; and tautomers, solvates and salts thereof. |