| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0bddb695331af9b1a351ec38b1476e85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d39573398ad3a0a5d94465e4356d024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3823cd687a1bac2412d019041d26df08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_095ec397b3b0ec4eac507b227ff4e6db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4df12f8cc519cfaa2a90ecdcb0ef8a15 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-48 |
| filingDate |
2010-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8c7e26dcc3ffcbbaa6a81cc93d715e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ef05a212c0eed4290e853ab4c3230d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b6ae0d8e78e96ae5a6630abedc06a03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfbf8a082f60da9e30d8bab61e70de83 |
| publicationDate |
2012-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8119639-B2 |
| titleOfInvention |
Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile |
| abstract |
Pharmaceutical compositions containing dihydroergotamine (DHE) and methods in which DHE is administered to patients for treatment of migraine without side effects or adverse effects are disclosed. Methods for rapid treatment of migraine with DHE are disclosed comprising: dampening the peak plasma concentration (C max ) and slightly delaying the peak such as to avoid activating the dopaminergic and adrenergic receptors, while achieving sufficient active binding to the serotonin receptors to provide relief from migraine symptoms within a timeframe that permits rapid resolution of migraine symptoms. Inhaler devices suitable for the methods are disclosed. Kits for practicing the methods of invention are disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10507295-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10537692-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11007332-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11395887-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10016582-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9550036-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11517548-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019247393-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10940278-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9833451-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11752100-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011082150-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11759585-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10172853-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9394314-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11266799-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11278492-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11730903-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11191910-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011171141-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9919117-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11185497-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11690819-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11571532-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010081664-A1 |
| priorityDate |
2007-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |