Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b88d3bc25a6c3f27d97bc6d67b46b1ab |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
filingDate |
1999-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2000-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0514089fb193cdf021296906c7ca695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15fa410d15264b783537a9ac5c62d4f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e7d1138810782002998614141422a9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_220a4bf56d30211f2e5884659843ccac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef06a2c4496af44e428495346022c7fd |
publicationDate |
2000-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6156339-A |
titleOfInvention |
Process for preparing solid pharmaceutical dosage forms |
abstract |
This invention relates to a process for the preparation of an oral solid rapidly disintegrating dosage form of a pharmaceutically active substance which has an unacceptable taste which process comprises: (i) forming a solution or a suspension in a solvent of a water soluble or water dispersible carrier, a filler and the pharmaceutically active substance with the unacceptable taste in association with a lipid, the weight ratio of the pharmaceutically active substance to the lipid being in the range of from 1:1 to 1:10 and the weight ratio of the carrier to the lipid being in the range of from 5:1 to 1:15; (ii) forming discrete units of the suspension or solution; and (iii) removing the solvent from the discrete units under conditions whereby unit dosages are formed comprising a network of carrier/filler carrying a dosage of the pharmaceutically active substance in association with the lipid; oral solid rapidly disintegrating dosage forms prepared by such a process are also provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10172853-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6918991-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011081387-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008063713-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9833451-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9616060-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8545879-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005112196-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005042286-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7811604-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008039433-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-20321887-U1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2322197-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2322198-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8080236-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7994197-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2322194-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2322195-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2322196-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8828359-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8529946-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8470301-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11786508-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004001885-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8148377-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8889184-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10251881-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004139624-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7354601-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004029843-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004224024-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004098561-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8119639-B2 |
priorityDate |
1997-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |