abstract |
A tasteless, granular, directly compressible, stable, fast-dissolving complex of a bitter tasting basic drug, pharmaceutical formulations comprising the tasteless complex of the basic drug and dosage forms thereof are disclosed. The basic drug can be fexofenadine, and the complex of the basic drug can be a fexofenadine-carbomer complex. Processes for preparing, isolating and characterizing the tasteless complex of the bitter tasting basic drug and processes for producing the pharmaceutical formulations are also disclosed. |