| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_095ec397b3b0ec4eac507b227ff4e6db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d39573398ad3a0a5d94465e4356d024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4df12f8cc519cfaa2a90ecdcb0ef8a15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3823cd687a1bac2412d019041d26df08 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-48 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06 |
| filingDate |
2008-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_807a610ca1fdc75955a77f3382822f34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72b2deef0a4366f8a29405891df0a2e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_225579a16ec128e7a2b333027b5af0d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b32b03a33006e97105c06e96ae1e2081 |
| publicationDate |
2008-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008287451-A1 |
| titleOfInvention |
Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile |
| abstract |
Pharmaceutical compositions containing dihydroergotamine (DHE) and methods in which DHE is administered to patients for treatment of migraine without side effects or adverse effects are disclosed. Methods for rapid treatment of migraine with DHE are disclosed comprising: dampening the peak plasma concentration (C max ) and slightly delaying the peak such as to avoid activating the dopaminergic and adrenergic receptors, while achieving sufficient active binding to the serotonin receptors to provide relief from migraine symptoms within a timeframe that permits rapid resolution of migraine symptoms. Inhaler devices suitable for the methods are disclosed. Kits for practicing the methods of invention are disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10758532-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003232876-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10172853-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11083712-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020123607-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8022095-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008118442-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11541043-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9833451-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010151804-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8119639-B2 |
| priorityDate |
2007-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |