| abstract |
The invention concerns a pharamceutical composition which comprises known or novel quinazoline derivatives of the formula In n wherein, for example, R¹ is hydrogen, trifluoromethyl or nitro, n is 1 and R² is halogeno, trifluoromethyl, nitro, cyano, (1-4C)alkyl, (1-4C)alkoxy, N -(1-4C)alkylamino, N , N -di-((1-4C)alkyl]amino, (1-4C)alkylthio, (1-4C)alkylsulphinyl or (1-4C)alkylsulphonyl; nand pharmaceutically-acceptable diluents or carriers thereof; the novel quinazoline deribatives and a process for their preparation; and the use of the receptor tyrosine kinase inhibitory properties of both the known and novel quinazoline derivatives in the treatment of cancer. |