Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63cb8d94afd0adc50b04cf17d36a1e78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e182bc931f3671c41d5bfff9125b2bf0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76e8b0ec2338a4a64112e7ad1ce2041d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 |
filingDate |
2008-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ffb879ce1cb67acb44595ac006b8ffc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_910f13556fd6cec429335446ce20dbb5 |
publicationDate |
2013-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8349854-B2 |
titleOfInvention |
Salts of 4-aniline quinazoline derivative |
abstract |
The present invention relates to salt forms of N-{4-[3-chloro-4-(3-fluoro-benzyloxy)phenylamino]-quinazolin-6-yl}-acrylamide as exemplified by formula (I), methods of preparation thereof, pharmaceutical compositions comprising the same and their use thereof. The salt forms of the present invention, which possess excellent tumor inhibitory activity, good bioavailability and low toxicity in an animal body, are suitable for use of preparation of anti-tumor medicaments. |
priorityDate |
2007-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |