abstract |
The invention relates to substituted nitrogen containing bicyclic heterocycles of the formula (I): wherein Z is CH 2 or N-R 4 and X, R 1 , R 2 , R 4 , R 6 , R 7 and n are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof. |