| abstract |
An object of the present invention is to provide an α, β-unsaturated amide compound having anti-cancer activity and the like, a pharmaceutically acceptable salt thereof and the like. An α, β unsaturated amide compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof etc. has anti-cancer activity etc .: wherein A has a substituent R.sup.1 represents a hydrogen atom or lower alkyl which may have a substituent, R.sup.2 is aryl which may have a substituent, or may have a substituent. A substituted or unsubstituted aliphatic heterocyclic group or an optionally substituted aromatic heterocyclic group, and X represents -O-, -S- or -SO2- , -NRX1- (wherein, RX1 represents a hydrogen atom or lower alkyl), -CHRX2- (wherein RX2 represents a hydrogen atom or hydroxy), -CH = CH-, -CO- or -NH And n1 and n2 are the same or different and each represents 0 or 1]. |