| abstract |
The subject of the present invention is a compound of the general formula (I) or (I ′) or a pharmaceutically acceptable salt thereof; a pharmaceutical composition comprising at least one of these compounds; At least one method of production; use of at least one of these compounds for the treatment and / or prevention of various cancers and / or proliferative disorders; monitoring the effectiveness of anti-cancer treatments for various cancers To the use of at least one of these compounds. In one embodiment, the subject matter relates to compounds that bind to heat shock protein 70 (Hsp70) at a certain level of specificity. In another embodiment, the subject matter relates to compounds that bind and inhibit at a level of specificity to both heat shock protein 70 (Hsp70) and heat shock cognate protein 70 (Hsc70). |