abstract |
The present invention relates to a polypeptide which: exhibits binding activity with respect to Fc regions of immunoglobulin G; can be suitably used for the detection, purification, immobilization, or elimination of antibodies, immunoglobulin G, or protein including Fc regions of immunoglobulin G; and comprises an amino acid sequence indicted in any of formulae (1)-(4) below: formula (1) (SEQ ID NO.: 1) Y-D-P-x-T-G-T-W-R-S-x-[IL]; formula (2) (SEQ ID NO.: 10) R-[QRS]-x-x-[GS]-Y-D-P-R-T-G-T-W-R-S-S-I-A-Y-G-G; formula (3) (SEQ ID NO.: 20) G-V-V-R-Q-W-S-G-x-x-x-x-x-x-x-x-R-S-S-I-A-Y-G-G; and formula (4) (SEQ ID NO.: 23) D-A-A-W-H-L-G-E-L-V-W-A-T-Y-Y-D-P-E-T-G-T-W-x-P-D-W-x-x-M (in the formulae, x represents any amino acid residue, and "[ ]" signifies any one of the amino acid residues presented within the "[ ]"). |