http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019172401-A1

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filingDate 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f394c289511a8c80fffe303eca03f18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_defb2a3364e6a93e6bbc4f77242517ed
publicationDate 2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019172401-A1
titleOfInvention Polypeptide mimicking denatured antibody
abstract The present invention provides a molecule that mimics the non-naturally-occurring three-dimensional structure of a denatured antibody, it being possible to use the molecule in quantitative evaluation of the denatured antibody. Specifically, the present invention provides a C-terminal deleted CH3 domain set forth in (i) or (ii): (i) a C-terminal deleted CH3 domain consisting of an amino acid sequence in which an amino acid is deleted within a range of 5-20 residues from the C-terminal side in an amino acid sequence represented by any of SEQ ID NOS: 1-7; or (ii) a C-terminal deleted CH3 domain consisting of an amino acid sequence in which an amino acid is deleted within a range of 5-20 residues from the C-terminal side in an amino acid sequence in which one or several amino acids in an amino acid sequence represented by any of SEQ ID NOS: 1-7 have been substituted, deleted, inserted, and/or added, an AF.2A1 polypeptide specifically binding to said C-terminal deleted CH3 domain.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021193870-A1
priorityDate 2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 44.