http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019172401-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60e66be87630d7cef0ce770e1d898eec |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-00 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00 |
filingDate | 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f394c289511a8c80fffe303eca03f18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_defb2a3364e6a93e6bbc4f77242517ed |
publicationDate | 2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2019172401-A1 |
titleOfInvention | Polypeptide mimicking denatured antibody |
abstract | The present invention provides a molecule that mimics the non-naturally-occurring three-dimensional structure of a denatured antibody, it being possible to use the molecule in quantitative evaluation of the denatured antibody. Specifically, the present invention provides a C-terminal deleted CH3 domain set forth in (i) or (ii): (i) a C-terminal deleted CH3 domain consisting of an amino acid sequence in which an amino acid is deleted within a range of 5-20 residues from the C-terminal side in an amino acid sequence represented by any of SEQ ID NOS: 1-7; or (ii) a C-terminal deleted CH3 domain consisting of an amino acid sequence in which an amino acid is deleted within a range of 5-20 residues from the C-terminal side in an amino acid sequence in which one or several amino acids in an amino acid sequence represented by any of SEQ ID NOS: 1-7 have been substituted, deleted, inserted, and/or added, an AF.2A1 polypeptide specifically binding to said C-terminal deleted CH3 domain. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021193870-A1 |
priorityDate | 2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.