| abstract |
Carbapenem derivatives having potent antimicrobial activities on MRSA, PRSP, influenza viruses and β-lactamase-producing bacteria and a high stability to DHP-1. Namely, compounds represented by the general formula (I) or pharmaceutically acceptable salts thereof, wherein R1 represents H or methyl; R?2 and R3¿ represent each H, halogeno, lower alkyl, etc.; R4 represents optionally substituted lower alkylthio, etc.; and R5 represents optionally substituted lower alkyl, etc. |