| abstract |
Novel carbapenem derivatives represented by general formula (I) which have an optionally substituted imidazo[5,1-b]thiazolium-6-ylmethyl group at the 2-position. The compounds have a broad and potent antibacterial activity on Gram-positive bacteria and Gram-negative bacteria including Pseudomonas aeruginosa and show a potent antibacterial effect on various β-lactamase-producing bacteria and MRSA and an extremely high DHP-1 stability. |