http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8785365-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb7e5a5d3da94e5a6d3a087318667f6c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9cd9a28c56324f2daca53ebd6314fd51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b82acac43cdcd5de981ea2294a5e9b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0bf0928b608797b70bbc2b91c7e52e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D3-38681 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2417 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11D3-386 |
| filingDate | 2007-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_046badb9f42fbd61a615065f7fa2263d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a9bc269fd3c88317486364eabf61676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8d8a36cff84b3a54ac1f9c14d5ff3b5 |
| publicationDate | 2014-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8785365-B2 |
| titleOfInvention | Alpha-amylase variants stabilized against dimerization and/or multimerization, method for the production thereof, and detergents and cleansers containing these alpha-amylase variants |
| abstract | The present invention relates to α-amylase variants that are stabilized to dimerization and/or multimerization, in particular at elevated temperatures or high pH, by point mutagenesis of positively polarized or charged or neutral surface amino acids to give more negatively polarized or charged amino acids. The invention further relates to methods of increasing the stability of an α-amylase to dimerization and/or multimerization brought about by electrostatic interactions whereby at least one amino acid residue on the surface of the starting molecule, which makes a neutral or positively polar or charged contribution to the electrostatic potential of said molecule, is replaced with a more negatively polar or negatively charged amino acid residue. The α-amylase variants obtained thereby exhibit better stability to influences of the solvent, increased processivity, and are suited for numerous industrial areas of use, in particular as active ingredients in detergents and cleansers. |
| priorityDate | 2004-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1309.