http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8563247-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a9d8cc98e6ac31065ddf6ac9fa256c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8195508fe3ab1e811b92f7e04b859baa |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2010-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0b4d82adf78b57f33954a5f3b6a374d |
publicationDate | 2013-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8563247-B2 |
titleOfInvention | Kits for multiplexed nucleic acid analysis by capture of single-stranded DNA produced from double-stranded target fragments |
abstract | A method of fragmentation of double stranded DNA is disclosed for use in nucleic acid analysis, notably in the multiplexed analysis of polymorphisms and mutations. The method produces a multiplicity of labeled sense and anti-sense fragments which are not complementary, and thus do not significantly re-anneal under conditions suitable for hybridization analysis (or capture-mediated elongation analysis) of the polymorphisms and/or mutations. The fragments display a desired or predicted length distribution. Cleavage sites can be selected such that the fragments are short, yet long enough to allow discrimination among fragments in an assay, and as a matter of statistical probability, such that the majority of fragments contain at least one labeled nucleotide to facilitate detection. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10752892-B2 |
priorityDate | 2003-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 497.