abstract |
The present invention teaches a novel approach to detecting and/or analyzing nucleic acid sequences. Generally, the invention relates to detecting and/or analyzing nucleic acid sequences using microsphere-based assays. More specifically, the invention relates to detecting and/or analyzing nucleic acid sequences using microsphere-based oligonucleotide ligation multiplexed assays. The present invention also provides methods and kits for performing microsphere-based oligonucleotide ligation assays, which include bound probes attached to addressable microspheres and free probes bearing a detectable label. |