| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0bc6df83ba6eddf48863258323edbb08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5de66fcc7c37934b48c684ca26e9cc0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63cd1e4db7d3148fd186b5ece044924a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4198442aa7a1f487673f43d2e26962bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_682ad1a35c060018b6274c33d495764a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-1335
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-346
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-155 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0658
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-185 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate |
2007-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c139259a8468eabbfb578fe4c4570caa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe2068a328cf2e9166f391247d6c58f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09b5a5a27eca13f8ee74df3bd6bbbb2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1750c5adfc063dd64c69e636de0444b7 |
| publicationDate |
2012-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8304398-B2 |
| titleOfInvention |
Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly or abnormally expressed gene |
| abstract |
The present invention provides means and methods for alleviating genetic disease. A genetic defect that has a phenotype in differentiated cells can lead to defects in precursor cells thereof. These so-called secondary defects contribute to the overall disease of the individual. In the present invention, genetic intervention with the aim to alleviate symptoms of genetic disease is directed toward the primary genetic defect in the differentiated cell and the secondary defect in the precursor cell. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9745559-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9890379-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11274299-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10689646-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10093707-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9926557-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10544416-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10876114-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10179912-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11208657-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10246707-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2796425-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11427820-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11268096-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10913946-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10190116-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10195249-B2 |
| priorityDate |
2006-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |