http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7906307-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_136cb56216d220f184305e921e1ac221 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6463 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6454 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L15-00 |
| filingDate | 2007-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1daf1b5901c9adfafa89f6049b74e1c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a25f7b5dbf259a5de1de69ef610254ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fdfda38f69e3a2b0d0a70dde705e201 |
| publicationDate | 2011-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7906307-B2 |
| titleOfInvention | Variant lipid acyltransferases and methods of making |
| abstract | The present invention relates to a method for the production of a variant lipid acyltransferase comprising the steps of: (i) selecting a parent enzyme which is a lipid acyltranserase enzyme; (ii) modifying one or more amino acids to produce a variant lipid acyltransferase; (iii) testing the activity of the variant lipid acyltransferase on a galactolipid and/or phospholipid and/or triglyceride substrate; (iv) selecting a variant enzyme with enhanced activity towards galactolipids compared with the parent enzyme; (v) providing a Bacillus licheniformis cell; (vi) transforming the Bacillus licheniformis cell with a heterologous nucleotide sequence encoding said variant lipid acyltransferase; and (iii) expressing said variant lipid acyltransferase in the cell under the control of a promoter sequence. The variant lipid acyltransferase can undergo post-translations modification, truncation and/or clipping, i.e., to remove a signal peptide. In addition, the present invention further relates to the use of Bacillus licheniformis to express a lipid acyltransferase, a Bacillus licheniformis host cell comprising a heterologous lipid acyltransferase and a vector comprising a nucleotide sequence encoding a lipid acyltransferase operably linked to a promoter sequence homologous to B. licheniformis. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017015233-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011171346-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8652809-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9228211-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010215803-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011136187-A1 |
| priorityDate | 2003-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 426.