abstract |
Animal feeds comprising a compound that produces an antimicrobial substance and a compound that disrupts the phospholipid layer of bacteria are disclosed. The compounds can act synergistically against bacteria, and therefore improve the growth or the feed conversion ratio of animals. The feed may be fed to monogastric and/or non-ruminant animals such as poultry, pigs, piglets, (veal) calves or fish. The compound producing an antimicrobial substance can be an enzyme such as an oxidase (e.g. glucose oxidase), peroxidase, lipoxygenase, synthase or phosphorylase and can generate a toxic substance such as phosphatidyl choline, hydrogen peroxide, HOCl, OSCN or xylitol-5-phosphate. The phospholipid disrupting compound can be a phospholipase, polyunsaturated fatty acid (PUFA, such as arachidonic acid) or a chelating agent (such as EDTA). |