http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7081551-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fec576c38e34882531ca37d6b922bf42 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C251-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-29 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C251-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-28 |
| filingDate | 2003-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba15a25b41e551976a3796b35b2afa60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c4ed235a24c9f51a0853592f0106dca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76572bc2100ee5c047e61235865eb2ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7516e201cee558b578dbe7e832ac8ed6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b05f6d361bbc3ab077dcf60a04ecc724 |
| publicationDate | 2006-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7081551-B2 |
| titleOfInvention | Optically active (R)-1-(4-trifluoromethylphenyl)ethylamine |
| abstract | Optically active (R)-1-(4-trifluoromethylphenyl)ethylamine is a novel compound as an important intermediate for medicines and agricultural chemicals. This compound can be obtained with high optical purity and high yield by a process including the steps of (a) a dehydrocondensation of 4′-(trifluoromethyl)acetophenone and an optically active (R)-1-phenylethylamine to obtain an optically active imine; (b) asymmetrically reducing the imine into an optically active secondary amine; (c) reacting the amine with an organic acid (phthalic acid or benzenesulfonic acid), thereby obtaining a product that is a phthalate of or benzenesulfonate of the amine; (d) subjecting the product of the step (c) to a hydrogenolysis, thereby obtaining a product that is a phthalate of or benzenesuilfonate of optically active (R)-1-(4-trifluoromethylphenyl)ethylamine; and (e) neutralizing the product of the step (d) into the optically active (R)-1-(4-trifluoromethylphenyl)ethylamine. |
| priorityDate | 2002-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 496.