http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6797842-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fec576c38e34882531ca37d6b922bf42 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-52 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-52 |
| filingDate | 2001-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba15a25b41e551976a3796b35b2afa60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b05f6d361bbc3ab077dcf60a04ecc724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7516e201cee558b578dbe7e832ac8ed6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaf522747765f87081b73100fcb4c76b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76572bc2100ee5c047e61235865eb2ef |
| publicationDate | 2004-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6797842-B2 |
| titleOfInvention | Process for producing optically active 1-(fluoro- or trifluoromethyl-substituted phenyl) ethylamine and process for purifying same |
| abstract | An optically active 1-(fluoro- or trifluoromethyl-substituted phenyl)ethylamine is produced with high optical purity and in an industrially simple and efficient manner by asymmetrically reducing an optically active imine, obtained by dehydration and condensation of a fluoro- or trifluoromethyl-substituted phenylmethyl ketone and an optically active primary amine under acidic conditions, using a hydride reducing agent to convert to an optically active secondary amine, and subjecting the secondary amine or its salt of an inorganic acid or organic acid to hydrogenolysis. In addition, an optically active 1-(fluoro- or trifluoromethyl-substituted phenyl)ethylamine is purified to an even higher optical purity in an industrially simple and efficient manner by converting the optically active secondary amine of the synthetic intermediate obtained by asymmetric reduction, or an optically active 1-(3,5-bis-trifluoromethylphenyl)ethylamine, one of the target compounds, to an inorganic or organic acid salt followed by recrystallization purification. This ethylamine is an important intermediate of pharmaceuticals and agricultural chemicals. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7081551-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004024253-A1 |
| priorityDate | 2000-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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