abstract |
PCT No. PCT/GB95/02030 Sec. 371 Date Feb. 21, 1997 Sec. 102(e) Date Feb. 21, 1997 PCT Filed Aug. 29, 1995 PCT Pub. No. WO96/06822 PCT Pub. Date Mar. 7, 1996The invention provides compounds of formula I: wherein A, B, D, X, R1, and R3 have any of the values defined in the specification, as well as N-oxides thereof, S-oxides thereof, pharmaceutically acceptable salts thereof, and in vivo hydrolizable esters and amides thereof, that are useful to relieve pain. The invention also provides pharmaceutical compositions as well as synthetic and therapeutic methods relating to such compounds. |