| abstract |
Novel pyrimidine, pyridine, pyridazine, pyrazine and triazine compounds are provided of the formula (I).n n The compounds of the invention are useful for treating hypertension, edema, renal failure, congestive heart failure, psoriasis and glaucoma, and in the prevention and treatment of atherosclerosis or to treat gastrointestinal disorders associated with enhanced contractility and/or motility of intestinal smooth muscle or to treat contractile disorders of the uterus. |