| Predicate |
Object |
| assignee |
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_843aed8ed300053780eef07918ab72dd |
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5156
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 |
| classificationCPCInventive |
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| classificationIPCInventive |
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| filingDate |
2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c21be8bbd75bfef439db25ba9442e74a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76ade4419364815303398988e7ce73c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f75e9849dc8387915098b7067dd0f5d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d0ce529cb9a666dcdd7c176ff5ee359
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e00d4b750c283e315fb95a73dbf87bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd53b988dacfc00bb4c95bd32d19568d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68945d0bccf3e3d165a3150b40af9383
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_173ab37b0363e945ff39d8caaa0bb012
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_044149df4cab414ecba4ea31503265d9 |
| publicationDate |
2022-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11365236-B2 |
| titleOfInvention |
Truncated NKG2D chimeric receptors and uses thereof in natural killer cell immunotherapy |
| abstract |
Several embodiments disclosed herein relate to the compositions comprising engineered Natural Killer (NK) cells that express a chimeric receptor, the chimeric receptor imparting to the NK cells an enhanced ability to target specific cells, such as cancerous cells or those affected by an infectious disease. Several embodiments relate to NK cells that target cells expressing natural ligands of NKG2D, where the NK cells comprise transmembrane and/or signaling domains that lead to cytotoxic and/or cytolytic effects when the NK cells bind a target cell. Uses of NK cell compositions to treat diseases are also provided for in several embodiments. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11560548-B2 |
| priorityDate |
2017-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |