Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_366f1cb3c7f4906b35a17d0c94decebb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca30438498a33c082e0710485cc0b86a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5152 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-99 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
filingDate |
2000-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_016ac53c0b7480ef26f8180af9539d93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b09093ba110332bc8e1888ecec192112 |
publicationDate |
2002-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1231262-A1 |
titleOfInvention |
Method of in vitro culture of lymphocytes and gene therapy compositions |
abstract |
The method for in vitro culture of lymphocytes involves incubatingnlymphocytes and cells with a particular gene expressed in a particular cancer cell linenor cells, which are deficient or lowered in expression of a class 1 antigen and thenparticular gene has already been expressed, to amplify mainly NK cells ornnon-MHC-bound or MHC-bound killer T cells and then to amplify killer T cells specificnto an antigen to a cancer. The in vitro culture of the lymphocytes can produce a groupnof lymphocytes composed mainly of killer cells. n The group of the lymphocytes so produced can be used for immune therapyneffective even for patients with cancer in the terminal stage to whom conventionalncancer treatment and cancer curing agents. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10774311-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11141436-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2666466-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2666466-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10801012-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11154575-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10538739-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11560548-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10836999-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10829737-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10428305-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11253547-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11365236-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10774309-B2 |
priorityDate |
1999-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |