| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-145 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate |
2018-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7298f503d0a8016a7bbce5fed65e8150
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9e95562b2dd75a0b3c2ae8ec3b0baf7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4574e4bafda67df42f0090ecaa736239
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d71a39c62a28a9d5e18b75ba3bf701e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83ac01fd157b044ff52b39cd3abc6cc2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74a5c024c6440f29444c207a610c4526
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24f7c52e755babaa96b6fcfc3ea38bd3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0abf8e9a0b15f8c049d7e309c7de42d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f8957121834211ac8dbb46471d868a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e53c8b5691ccee637bd4e90abf8f2dae |
| publicationDate |
2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10982198-B2 |
| titleOfInvention |
Compositions and methods relating to a mutant Clostridium difficile toxin |
| abstract |
In one aspect, the invention relates to an immunogenic composition that includes a mutant Clostridium difficile toxin A and/or a mutant Clostridium difficile toxin B. The mutant toxin may include a glucosyltransferase domain having at least one mutation and a cysteine protease domain having at least one mutation, relative to the corresponding wild-type C. difficile toxin. The mutant toxins may include at least one amino acid that is chemically crosslinked. In another aspect, the invention relates to methods and compositions for use in culturing Clostridium difficile and in producing C. difficile toxins. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11208633-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11535652-B2 |
| priorityDate |
2012-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |