| abstract |
Immunogenic compositions containing ceramide or ceramide analogs for treating or reducing the risk of developing one or more symptoms of a disease or disorder associated with ceramide-induced cell death are provided. The immunogenic compositions contain immunogenic ceramide, and, optionally, pharmaceutically acceptable excipients and one or more additional adjuvants. Methods of using the disclosed immunogenic ceramide compositions for reducing ceramide-induced cell death are provided. Methods of using the disclosed immunogenic ceramide compositions therapeutically or prophylactically for treating or reducing the risk of developing one or more symptoms of a disease or disorder associated with ceramide-induced cell death are also provided. |