| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_066828a4b6f7a816447cb8ba1bcbb40e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 |
| filingDate |
1993-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d87bcea26b77493d2aef3dd7f9eed6e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a864b6a825de199288c649f9efdbac6e |
| publicationDate |
1996-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5530103-A |
| titleOfInvention |
Method for the purification of PC protein from Borrelia burgdorferi |
| abstract |
A method of purifying B. burgdorferi proteins comprising the steps of (a) disrupting a B. burgdorferi cell and fractionating the disrupted cell into membrane and cytoplasmic components; (b) resuspending the membrane component in a non-denaturing detergent thereby producing a solubilized protein and an insolubilized material and then separating said solubilized protein from said insolubilized material; (c) subjecting the solubilized protein to ion-exchange chromatography so as to produce protein fractions; and (d) assaying the protein fractions to identify those fractions which contain proteins of interest wherein the purified proteins of interest are in a biologically active form suitable for use in vaccines, is disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8668939-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9226956-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8734861-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE46376-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE46518-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE48863-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004126383-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8137678-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10982198-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8043635-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8414901-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8277852-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011212190-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10597428-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008181916-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6303129-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005181079-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006029608-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6316005-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003175235-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009185990-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8663712-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8900597-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9745354-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8318220-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10774117-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6045804-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11208633-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10787652-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7442391-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6087097-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10004777-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9187536-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6667038-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11535652-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7473435-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8101212-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6872550-B1 |
| priorityDate |
1991-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |