Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3dded61bd89f99900518597c0958b9a9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-32 |
filingDate |
2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31e0213f323b93aa1e4e91a4742c2562 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d11e474d267a0cd589c4dee15b3153c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d01c1028e933e6f79d1c5cbb21da9e0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6bc0d76150b583d530521f4eecf9ec1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c456b758298dcd40d0aa1af8fde5386 |
publicationDate |
2020-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10703728-B1 |
titleOfInvention |
Crystalline form of olaparib and a process for preparing the same |
abstract |
In certain aspects, the invention provides a novel crystalline form of olaparib (4-[(3-[(4-cyclopropylcarbonyl)piperazin-4-yl]carbonyl)-4-fluorophenyl]methyl(2H)phthalazin-1-one). In related aspects, the invention provides a processe for preparing the novel crystalline form of olaparib. The process includes forming a solution comprising crude olaparib and an organic solvent; adding the solution to an anti-solvent to form a slurry comprising a precipitate; isolating the precipitate; and drying the precipitate to obtain a crystalline form III of olaparib. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111995582-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111995582-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111689905-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111689905-B |
priorityDate |
2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |