| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_266f27c9e90e00b1173c45726524c540
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3dded61bd89f99900518597c0958b9a9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-32 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-32 |
| filingDate |
2017-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_125dd28640a6dbf63f795064b638da09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0003d5ddc1e3d96677860b5670173fdf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_271ce726eee83e5fb6a84614ec18c6e7 |
| publicationDate |
2017-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2017123156-A1 |
| titleOfInvention |
Crystalline forms of olaparib and manufacturing processes therefor |
| abstract |
In certain aspects, the invention provides crystalline forms of olaparib (4-[(3-[(4- cyclopropylcarbonyl)piperazin-4-yl]carbonyl)-4-fluorophenyl]methyl(2 H )phthalazin- 1 -one). In related aspects, the invention provides processes for preparing the crystalline forms of olaparib. The processes include: forming a solution comprising crude olaparib and an organic solvent; adding an anti-solvent to the solution to form a slurry comprising a precipitate; isolating the precipitate; and drying the precipitate to obtain a crystalline form I of olaparib or a crystalline form II of olaparib. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022090938-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022058785-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111718300-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020531522-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10703728-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023084311-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10662178-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021220120-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022215034-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023017393-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10138211-B2 |
| priorityDate |
2016-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |