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publicationDate 2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2014206389-A
titleOfInvention Sample preparation method and mass spectrometry method for mass spectrometry
abstract A method for pretreatment of a biological sample for examining the distribution of a drug in a biological sample or quantifying the drug in the biological sample using matrix-assisted laser desorption / ionization (MALDI). A step of forming a matrix crystallite on the surface of the biological sample containing the drug by depositing the matrix on the biological sample, and further dispensing a matrix solution on the biological sample; A method for preparing a sample for mass spectrometry, which comprises a step of growing a matrix crystal on the microcrystal by spraying. [Effect] This method is particularly useful when performing imaging mass spectrometry in clinical trials. [Selection] Figure 2
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