abstract |
Described herein are compounds that modulate pyruvate kinase M2 (PKM2) and compositions comprising the compounds. Also described herein are methods of using compounds that modulate PKM2 in the treatment of cancer. Also, pharmaceutical compositions comprising the compounds provided herein, and pyruvate kinase function (eg, PKM2), including, for example, cancer, diabetes, obesity, autoimmune disorders, and benign prostate hyperplasia (BPH). Use of such compositions in methods of treating diseases and conditions associated with (function) is provided. |