| abstract |
Novel compounds, compositions and methods are provided that inhibit kinase activity associated with tumorigenesis in human or animal subjects. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one serine / threonine kinase or receptor tyrosine kinase. The novel compounds and compositions can be used alone or in combination with drugs for treating disorders mediated by at least one serine / threonine kinase or receptor tyrosine kinase, such as cancer. |