http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110387360-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01176 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 |
| filingDate | 2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110387360-B |
| titleOfInvention | Hydroxysteroid dehydrogenase and application thereof in synthesis of ursodeoxycholic acid precursor |
| abstract | The invention relates to hydroxysteroid dehydrogenase and application thereof in synthesis of ursodeoxycholic acid precursor. In particular, the method of manufacturing a semiconductor device,the invention discloses 12 alpha-hydroxysteroid dehydrogenase derived from rhodococcus and a mutant thereof, a coding gene and an amino acid sequence thereof, a recombinant expression vector and a recombinant expression transformant containing the gene, and application of catalyzing 12 alpha-hydroxysteroid to be oxidized into 12-carbonyl steroid by utilizing the hydroxysteroid dehydrogenase. Compared with the prior art, the recombinant steroid dehydrogenase catalytic oxidation reaction used in the invention is NAD + The coenzyme-dependent type has the advantages of low coenzyme application cost, simple operation, mild reaction conditions, environmental friendliness, high yield and the like, so that the coenzyme-dependent type has a good prospect in the application of producing and preparing the ursodeoxycholic acid precursor by taking cholic acid as a raw material. |
| priorityDate | 2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 245.