| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1966f3c715acc0fa006db05d916301a7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01225
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-0105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01159
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-02 |
| filingDate |
2015-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41ed5187331db77e91b45dd6b94092ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9c688240a59de94b0c588d8042ca659 |
| publicationDate |
2016-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016023933-A1 |
| titleOfInvention |
3-alpha-hydroxysteroid dehydrogenase mutants and process for the preparation of ursodeoxycholic acid |
| abstract |
The invention relates to novel 3α-hydroxysteroid dehydrogenase mutants, to sequences which code for these enzyme mutants, to methods for producing the enzyme mutants, and to the use thereof in enzymatic reactions of cholic acid compounds, and in particular in the production of ursodeoxycholic acid (UDCA). The invention further relates to novel processes for the synthesis of UDCA using the enzyme mutants; and to the production of UDCA using recombinant microorganisms which have been subjected to multiple modifications. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235122-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018036982-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110387360-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235122-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110387360-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107841489-A |
| priorityDate |
2014-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |