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filingDate 1999-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9976e5ebfd0cea7f91b5fdc9c01f11e
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publicationDate 1999-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9946386-A1
titleOfInvention ALK-1 RESPONDS TO TGF-β AND SIGNALS THROUGH SMAD-1 AND SMAD-5
abstract The invention relates to the molecule referred to as ALK-1, and its role as a type I receptor for members of the TGF-β family. The molecule has a role in the phosphorylation of Smad-5 and Smad-1, which also act as activators of certain genes. Aspects of the invention relate to this interaction.
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