| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96cf050a6d4943c33ddd5b9cc2d7ea8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_757a0fe8ea50d689ff270bd63cf4665e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20070fd36b4566fdea450051d6b36315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0cf3371a9dd0e2fab14e900377fd1096 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2334-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-968 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D219-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5765 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-572
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-532
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-576
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D219-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-447 |
| filingDate |
1997-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9321a99e4be28442fa91f82c9ee0dbb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fface16e5f96441fdcf0e82dc3e43487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be7b0465b3ae84d8295474ed74524d92 |
| publicationDate |
1997-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9726245-A1 |
| titleOfInvention |
Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes |
| abstract |
Novel heterocyclic compounds which generate chemiluminescence on reaction with a phosphatase enzyme are provided as well as a process for their preparation and intermediates useful therein. The compounds comprise a nitrogen, oxygen or sulfur-containing heterocyclic ring system bearing an exocyclic carbon-carbon double bond. The double bond is further substituted at the distal carbon with a phosphate group and an oxygen or sulfur atom-containing group. Novel compositions further comprising a cationic aromatic compound (CAC) in addition to the heterocyclic phosphate compound are provided. The addition of the CAC in the composition greatly increases the production of chemiluminescence and provides improved detection sensitivity. Compositions further comprising an anionic surfactant and a non-ionic surfactant provide additional improvements in detection sensitivity. The novel chemiluminescent compounds and compositions are useful in methods for producing light and in assays for phosphatase enzymes and enzyme inhibitors and in assays employing enzyme-labeled specific binding pairs. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7459284-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9940161-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-760023-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4790905-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5922558-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5965736-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9914358-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001516589-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6017769-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2004200649-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104230804-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7097995-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1015461-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6783948-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1015461-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1008600-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9966328-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9966005-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0200726-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1008600-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-760023-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1119554-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1119554-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002518410-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5772926-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016030711-A1 |
| priorityDate |
1996-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |