| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f97f0fa258a008bf056ad04b7f380dda |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-2105 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6424
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-14 |
| filingDate |
2015-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d0d3e565f3c6eaf94f672fef83c25ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21b30d1cd9bff9f121abd11191304483 |
| publicationDate |
2016-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2016143223-A1 |
| titleOfInvention |
Immobilized protease with improved resistance to change in external environment |
| abstract |
The present invention addresses the problem of providing a highly active protease that can be used in the preparation of a sample for mass spectrometry of a protein and has excellent stability with respect to changes in the external environment. The present invention provides: an immobilized protease that is characterized in that a crudely purified protease or a protease that has not been subjected to autolysis resistance treatment is immobilized on a nanoparticle surface; and a method for producing said immobilized protease. Since this immobilized protease can maintain high activity without being subjected to a change in the external environment, said protease is effective, for example, in preparing a sample to be supplied for mass spectrometry of a protein in a clinical specimen. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019130549-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2019130536-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2019130549-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019130536-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11209392-B2 |
| priorityDate |
2015-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |