http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2019130536-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-72 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 |
| filingDate | 2017-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2019130536-A1 |
| titleOfInvention | Simplified quantification method for monoclonal antibodies |
| abstract | The present invention presents the following steps: (a) capturing the monoclonal antibody in the sample and immobilizing it in the pores of the porous body, (b) the porous body on which the monoclonal antibody is immobilized, and the protease. The steps of contacting the immobilized nanoparticles with selective protease digestion of the monoclonal antibody over 30 minutes, and (c) liquid chromatograph mass analysis (LC-MS) of the peptide fragments obtained by selective protease digestion. ) Is a method for detecting a monoclonal antibody in a sample, which comprises the step of detecting the monoclonal antibody in the sample, wherein step (b) is carried out under stirring conditions for 10 seconds to 5 minutes at the beginning of the reaction and then standing conditions. Provide a way to do it. INDUSTRIAL APPLICABILITY According to the present invention, the method for detecting a monoclonal antibody using mass spectrometry can be simplified and applied to multi-sample analysis. |
| priorityDate | 2017-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.