| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_671d008452921a0d439716af976cadae |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-165 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-48 |
| filingDate |
2012-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f5aac66be90605d167fa78e754652ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08e4bf5614cc8ca2964f540fccc6eb86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df32cd72b5419a4b263568e4bc04dd3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6dae1ef0d522fd80d926b0606348820
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_495343291d0a502e098495ff72dd2eaa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd4e0abb63f2275eb626b3253e977a87 |
| publicationDate |
2013-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013092776-A1 |
| titleOfInvention |
Novel prongf mutants and uses thereof in the production of beta-ngf |
| abstract |
The present invention relates to a proNGF mutant and to uses thereof, in particular the use of a proNGF mutant for producing human beta-NGF. The present invention discloses a method of preparing a biologically active human beta-NGF from an inactive insoluble proNGF mutant. A proNGF mutant of the invention is substituted by any amino acid but not Arg or Lys at the native protease cleavage site R 1 SK 3 R 4 at least at positions R 1 and K 3 corresponding to positions 101 and 103 of the human wildtype proNGF sequence. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-201900014646-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015038582-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3406259-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020058217-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018215414-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019207106-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022090339-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11084854-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3991711-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10308694-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022221351-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3783013-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9617322-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021052926-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4039269-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022167607-A1 |
| priorityDate |
2011-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |