| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66106a75479d844dc7d7499a42289e34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5621b7dff9bb04ad7a7c33abf4db0246
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_611db4e62bfcb1ddd5159c44b51900e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef1b2f9dd9ee7f0571ca08f9af333a72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1229111a198f86af4112ecd730b55cd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6216e11c9f43b2fdf5a9a251f8df62e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b088a0e8b3e2f735ff69588d3ed73a6c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-48 |
| filingDate |
2012-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_086a2b23636b58234a080d857870e776
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1b9f73fed23b2cc8be23553163c9e1d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afede1439e9e2aeef23c2c9dfb39448f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be81c752fddc97f72273cbc3818275a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3439d2ce4c083c55bfbc3bb561a24b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c4601562541a90632a9f080c657700c |
| publicationDate |
2017-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9617322-B2 |
| titleOfInvention |
ProNGF mutants and uses thereof in the production of beta-NGF |
| abstract |
The present invention relates to a proNGF mutant and to uses thereof, in particular the use of a proNGF mutant for producing human beta-NGF. The present invention discloses a method of preparing a biologically active human beta-NGF from an inactive insoluble proNGF mutant. A proNGF mutant of the invention is substituted by any amino acid but not Arg or Lys at the native protease cleavage site R 1 SK 3 R 4 at least at positions R 1 and K 3 corresponding to positions 101 and 103 of the human wildtype proNGF sequence. |
| priorityDate |
2011-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |