| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9cf324aefdedd9a48bd670a3d428d622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2981b2ea94bb978c189207c1d3380e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6171684de68ce62ef3fbf1655618249
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0c281d8181c4e2311b865068c7d689d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0c22c416ac42202733599e9c867e81b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53d61bff624c8b7fbdb6bf48d86d14da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c327880de7bc6e87274c030939c79e6e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 |
| filingDate |
2010-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4458dab6478751794aef2b6654d0ed1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee4a915ca99bf5b19a07338b1fb41753
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54e217e6497b781fcc2a4f7a63842b47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65182f2464bc1d246c4c784f6cda8997
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fefe012870122ee2d3531ebab1a08da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_560d646e8a149aa97f6e1e9448e91876 |
| publicationDate |
2011-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2011142514-A1 |
| titleOfInvention |
Composition containing pias3 as an active ingredient for preventing or treating cancer or immune disease |
| abstract |
The present invention relates to a composition containing PIAS3 as an active ingredient for the prevention or treatment of cancer or immune disease. More specifically, the present invention relates to a composition containing the PIAS3 gene or an expression protein thereof as an active ingredient for the prevention or treatment of cancer or immune disease, to an immunosuppressant composition, to a method for reducing or inhibiting undifferentiated T cells into Th17 cells using the PIAS3 gene or an expression protein thereof, and to a method for activating regulatory T cells. The PIAS3 according to the present invention is excellent in inhibiting the differentiation of cytotoxic Th17 cells which produce and secrete inflammatory cytokines and in activating regulatory T cells (Tregs) having characteristics that inhibit the function of abnormally activated immune cells and control inflammatory responses. Thus, the PIAS3 may be useful as a pharmaceutical composition or immunosuppressant which may prevent or treat cancer or immune disease caused by the dysregulation of immune responses. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103114104-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103114104-B |
| priorityDate |
2010-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |